References
- Bitter T. et al, EJHF, 2009
- Oldenburg O et al. Circ J 2012
- Lanfranchi PA et al. Circulation. 2003
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Congestive heart failure (CHF) is a syndrome that affects around 10% of people aged over 65.*
Up to 50% of heart failure patients experience moderate to severe sleep-disordered breathing (SDB),1 with either Central Sleep Apnea (CSA), Cheyne-Stokes respiration (CSR), Obstructive Sleep Apnea (OSA) or a combination of all those.2
CSR occurs when periods of hyperventilation and hypoventilation (in a waxing/waning breathing pattern) alternate with periods of central hypopnoea/apnea.
CSR is a common form of SDB in patients with severe left ventricular dysfunction.3
It’s expected that SDB in general and CSR accelerates the progression of heart failure by causing:
Fragmented sleep resulting from CSR also causes fatigue and daytime sleepiness, which impacts quality of life.
Learn more about the treatment options for patients with CSR.
A large study on MediCare newly diagnosed HF patients has shown that those with SDB have a worse prognosis compared to those without.5
Nocturnal CSA/CSR in itself is associated with increased mortality6 in CHF patients.