Noninvasive ventilation for neuromusclar diseases in adults

A number of chronic neuromuscular disorders such as muscular dystrophy and motor neurone disease lead to progressive respiratory muscle dysfunction, which in turn can lead to respiratory failure and death. Nocturnal and daytime noninvasive ventilation (NIV) is becoming the preferred method of treatment for these disorders1, and should be considered for:

  • Patients with observed sleep-disordered breathing or night time oxygen desaturation1,2
  • Patients with progressive respiratory muscle weakness who develop hypoventilation (shallow breathing) and Obstructive Sleep Apnoea (OSA)3,4

Noninvasive ventilation as a treatment for neuromuscular disease has several benefits. It has been shown to1,5,6 :

  • Improve blood gases
  • Decrease work of breathing
  • Improve symptoms of fatigue
  • Reduce daytime sleepiness
  • Improve morning headaches
  • Improve survival in Duchenne muscular dystrophy (DMD) and amyotrophic lateral sclerosis (ALS) patients7,8

Find out more about noninvasive ventilation on our dedicated ResMed page

More Articles

Noninvasive ventilation for acute respiratory failure
Non-invasive ventilation (NIV) is often used for patients with Chronic Obstructive Pulmonary Disease, but emerging evidence suggests that NIV can be used in treating other types of acute respiratory failure.
Noninvasive ventilation for COPD patients
Treatment of COPD with noninvasive ventilation (NIV) has been shown to be effective in treating acute exacerbations of COPD, assisting pulmonary rehabilitation in COPD patients, and providing benefits in managing chronic hypercapnic COPD patients.
Noninvasive ventilation for obesity hypoventilation syndrome
Non-invasive ventilation in patients with obesity hypoventilation syndrome has been shown to normalise blood gases, prolong survival and increase exercise capacity.
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